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NanoKar Therapeutics Announces Formal Appointment of Craig Mosman as Chief Executive Officer

Mosman to lead NanoKar’s next phase of translational validation, partner readiness, and strategic collaboration for its ITAM optimization platform

— NanoKar Therapeutics, an early-stage biotechnology company developing intracellular signaling optimization technology for CAR-based cell therapies, today announced the formal appointment of Craig Mosman, J.D., as Chief Executive Officer.

Mosman will lead NanoKar’s partnership strategy and translational data priorities as the company advances research from the University of Utah laboratory of Matt Bettini, Ph.D. toward a partner-ready cell therapy platform. His appointment reflects NanoKar’s next phase of work: building the evidence, relationships, and development path needed to position the company’s ITAM optimization platform for potential commercialization with CAR-T, cell therapy, and biopharmaceutical partners.

“I’ve been fortunate throughout my career to work closely with scientific discoveries at the point where they begin to move from possibility to application. Dr. Bettini and his team have developed a compelling platform, and I’m grateful for the opportunity to help advance his work toward practical and rapid integration into existing and next-generation CAR-T programs. The goal is to give this discovery the strongest possible path to reach more patients over time.”

Craig Mosman, J.D. · Chief Executive Officer

Mosman brings experience across biotechnology, genomics, molecular biology, global health, law, and entrepreneurship, with a track record of advancing early-stage technologies through strategic partnerships. Before NanoKar, he co-founded Seek Labs, where he held senior leadership roles spanning business development, legal affairs, intellectual property strategy, and strategic collaborations.

“Craig’s experience sits precisely at the intersection of science and strategic execution. His ability to position emerging platforms for partnership makes him uniquely suited to lead NanoKar at this stage.”

Matt Bettini, Ph.D. · Co-Founder & Chief Scientific Officer

NanoKar’s proprietary ITAM optimization platform is designed to tune intracellular CAR signaling to improve persistence, reduce toxicity, and expand the potential for efficacy in solid tumors. The platform is intended to integrate into existing and next-generation CAR architectures without requiring changes to antigen targeting, co-stimulation, or manufacturing workflows.

The company is advancing its preclinical platform, generating additional validation data, and engaging potential licensing, co-development, and strategic partners. Its pipeline includes programs across hematologic malignancies and solid tumors, including CD19, HER2, GD2, Nectin4, EGFRvIII, and B7-H3-directed approaches.

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About NanoKar Therapeutics

NanoKar Therapeutics, Inc. is a biotechnology company focused on developing next-generation CAR-T cell therapies. Founded on breakthrough research from the University of Utah, NanoKar’s proprietary platform technology is designed to overcome the key limitations of current CAR-T therapies, including T-cell exhaustion and limited efficacy against solid tumors. The company is committed to advancing its platform through strategic partnerships and clinical development to bring transformative cell therapies to patients in need.

For more information, visit www.nanokartherapeutics.com.

Media Contact

NanoKar Therapeutics, Inc. craig@nanokartherapeutics.com

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Forward-Looking Statements

This press release contains forward-looking statements regarding NanoKar Therapeutics, Inc., including statements about the company’s research and development programs, the potential of its ITAM optimization platform, anticipated preclinical and clinical milestones, intellectual property, and plans for partnerships, financing, and commercialization. These statements are based on current expectations and assumptions and are subject to risks and uncertainties, including but not limited to risks associated with preclinical and clinical research, the timing and outcome of regulatory submissions and approvals, the success of clinical trials, manufacturing and supply, intellectual property protection and freedom to operate, competitive products and technologies, and the availability of financing on acceptable terms. Actual results may differ materially from those expressed or implied. NanoKar Therapeutics undertakes no obligation to update any forward-looking statement except as required by law. Nothing in this press release constitutes an offer to sell or a solicitation of an offer to buy any securities, and no securities of NanoKar Therapeutics may be offered or sold in any jurisdiction in which such offer or sale would be unlawful.